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. 2010 Dec 29;6(6):919–925. doi: 10.5114/aoms.2010.19302

Table I.

Comparative data of FEV %, PEFR%, serum nitric oxide (NO) and Eosin% at baseline and 8 weeks after treatment

Group 1 (n = 11) (Montelukast) Group 2 (n = 11) Fluticasone) Group 3 (n = 10) (SR-Theophylline) Group 4 (n = 7) (No medication)
Baseline Day 56 Baseline Day 56 Baseline Day 56 Baseline Day 56
X¯± SD X¯± SD X¯± SD X¯± SD X¯± SD X¯± SD X¯± SD X¯± SD
Age 10.0 ±1.95 9.7 ±2.01 9.6 ±0.97 9.9 ±2.91
FEV1% 68 ±10* 78 ±13* 72 ±15 81 ±11 76 ±9* 86 ±11* 75 ±14 73 ±21
PEFR% 63 ±17* 76 ±11* 59 ±15* 75 ±15* 65 ±18 73 ±11 67 ±19 62 ±17
NO [μmol/l] 4.9 ±3.9* 2.2 ±2.1* 3.2 ±2.5* 1.4 ±1.7* 3.7 ±2.4 2.3 ±2.7 2.4 ±3.6 4.5 ±5.2
Eosin% 6.0 ±2.0* 3.0 ±1.0* 9.0 ±4.0* 4.0 ±3.0* 5.0 ±3.0* 2.0 ±2.0* 3.0 ±2.0 2.0 ±1.0

* p = significant (p < 0.05) improvement in parameter after 8 weeks of treatment; for FEV % p = 0.007 and 0.012 (in groups 1 and 3 respectively for PEFR% p = 0.028 and 0.003 (in groups 1 and 2 respectively); for NO p = 0.041 and 0.026 (in groups 1 and 2 respectively); and for Eosin% p = 0.001, 0.000 and 0.002 (in groups 1, 2 and 3 respectively)

FEV1%–forced expiratory flow rate at first second as percentage of that predicted, PEFR%–peak expiratory flow rate as percentage of tha predicted, Eosin%–eosinophil count as percentage of eosinophils