Table II.
Distribution of TRAIL 1595 C/T genotypes according to clinical parameters and tumour characteristics of breast cancer patients
| N | % | CC (%) | CT (%) | TT (%) | |
|---|---|---|---|---|---|
| Age ≤45 years | 12 | 22.6 | 4 (33.3) | 7 (58.3) | 1 (8.3) |
| Age >45 years | 41 | 77.4 | 22 (53.7) | 14 (34.1) | 5 (12.2) |
| Family history of breast cancer | |||||
| Yes | 12 | 22.6 | 8 (66.7) | 3 (25) | 1 (8.3) |
| No | 41 | 77.4 | 18 (43.9) | 18 (43.9) | 5 (12.2) |
| Tumour (T) stage | |||||
| T1 | 14 | 26.4 | 7 (50) | 6 (42.9) | 1 (7.1) |
| T2 | 25 | 47.2 | 11 (44) | 13 (52) | 1 (4) |
| T3 | 10 | 18.9 | 5 (50) | 2 (20) | 3 (30) |
| T4 | 4 | 7.5 | 3 (75) | 0 (0) | 1 (25) |
| Lymph node status | |||||
| N0 | 14 | 26.4 | 7 (50) | 6 (42.9) | 1 (7.1) |
| N1 | 23 | 43.4 | 12 (52.2) | 9 (39.1) | 2 (8.7) |
| N2 | 13 | 24.5 | 6 (46.2) | 5 (38.5) | 2 (15.4) |
| N3 | 3 | 5.7 | 1 (33.39) | 1 (33.3) | 1 (33.3) |
| Distant metastasis | |||||
| (+) | 3 | 5.7 | 2 (66.7) | 1 (33.3) | - |
| (−) | 50 | 94.3 | 24 (48) | 20 (40) | 6 (12) |
| Oestrogen receptor | |||||
| (−) | 6 | 13.0 | 4 (66.7) | 2 (33.3) | – |
| (+) | 40 | 87.0 | 18 (45) | 17 (42.5) | 5 (12.5) |
| Progesterone receptor | |||||
| (−) | 7 | 15.2 | 4 (57.1) | 3 (42.9) | – |
| (+) | 39 | 84.8 | 18 (46.2) | 16 (41) | 5 (12.8) |