Table 1.
Patients’ characteristics and clinical data
| With/Without | SD | P | ||
|---|---|---|---|---|
|
|
||||
| H1N1 positive | H1N1 negative | |||
| Age (years) | 38.65 | 57.90 | 16.974/23.645 | <0.001 |
| Chest X-ray with findings upon admission | 42 (31.6%)/91 (68.4%) | 103 (100%)/0 (0%) | <0.001 | |
| Days under oseltamivir | 5.4 | 42.00 | 2.542/0.00 | <0.001 |
| Days of hospitalization | 6.32 | 8.05 | 3.336/4.418 | NS |
| Patients with obesity | 68 (51.1%)/65 (48.9%) | 54 (52.4%)/49 (47.6%) | NS | |
| PO2 upon admission (mmHg) | 74.83 | 65.55 | 13.888/14.156 | NS |
| SPO2 upon admission (mmHg) | 94.62 | 93.06 | 12.308/16.64 | 0.001 |
| Sex (male/female) | 77/56 (57.9%/42.1%) | 57/46 (55.34%/44.66%) | NS | |
| Patients administered macrolides | 96 (72.2%)/37 (27.8%) | 60 (58.3%)/43 (41.7%) | 0.005 | |
| Patients administered quinolones | 53 (39.8%)/80 (60.2%) | 43 (41.7%)/60 (58.3%) | NS | |
| Patients changed/added quinolones from/to macrolides* | 16/96 | – | ||
| Respiratory distress upon admission | 20 (15%)/113 (85%) | 52 (50.5%)/51 (49.5%) | <0.001 | |
| Patient with respiratory disease background | 46 (34.5%)/87 (65.4%) | 33 (32%)/70 (67.9%) | NS | |
| Intensive care unit admission | 9 (6.7%) | 4 (3.8%) | NS | |
| Asthma | 22 (16.5%) | 9 (8.7%) | ||
| COPD | 21 (15.7%) | 24 (23.3%) | ||
| IPF | 3 (2.2%) | – | ||
| CHF | 18 (13.5%) | 44 (42.7%) | ||
| DM | 20 (15%) | 20 (19.4%) | ||
| Cancer | 10 (7.5%) | 6 (5.8%) | ||
Note:
*
Patients had to change or add their antibiotic treatment.
Abbreviations: CHF, coronary heart failure; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; IPF, interstitial pulmonary fibrosis; SD, standard deviation.