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. 2012 Mar 13;7(3):e33057. doi: 10.1371/journal.pone.0033057

Figure 12. Motor behavioral effects in rats exposed to manganese and Trolox™.

Figure 12

The animals were tested in the circular open field for 10 min to evaluate possible motor changes induced by different treatments used. The panels show the parameters analyzed from rats treated for five days (PN8-12) with saline (control; NaCl 0.9%), MnCl2 20 mg/kg (Mn), Trolox™ 1 mg/kg (Tr) or MnCl2 20 mg/kg plus Trolox™ 1 mg/kg (Mn + Tr). Panel (A) show the distance (m), (B) speed (m/s), (C) grooming frequency and (D) rearing frequency. Results represent mean ± S.E.M derived from twelve independent experiments. Statistical analysis was performed by ANOVA followed by Newman-Keuls test. * p<0.05 compared to control; # p<0.05 compared to MnCl2 20 mg/kg group.