Table 2. Characteristics of significant LOD-score loci identified by genome-wide linkage in the MO1 family.
| Chrom | 7 | 7 | 13 | 13 | ||||
| Cytoband | 7p21.1 | 7p15.3 | 7q21.3 | 7q22.2 | 13q14.12 | 13q14.3 | ||
| LOD max | 3.257 | 3.257 | 3.257 | 3.257 | ||||
| # of SNPs | 297 | 643 | 25 | 27 | ||||
| Flanking SNP | rs13222101 | rs7806550 | rs11768589 | rs17152355 | rs4245330 | rs2248414 | rs536338 | rs797493 |
| Position (cM) | 31.654 | 34.696 | 106.189 | 115.436 | 47.21 | 47.495 | 53.166 | 53.377 |
| Size (cM) | 3.042 | 9.247 | 0.285 | 0.211 | ||||
| Position (bp, in GRCh37) | 17723272 | 20278642 | 95615196 | 105575202 | 44661321 | 44798197 | 51103461 | 51261023 |
| Size (Mb) | 2.56 | 9.96 | 0.14 | 0.16 | ||||
| Homozyg. | YES | YES | NO | NO | ||||
| # of genes | 11+5 pseudogenes | 166+39 pseudogenes | 1 hypothetical | 1 (2 terminal exons) | ||||
| Candidate Genes | SHFM1, DLX5, DLX6 | |||||||
The flanking SNPs are the first ones outside the LODmax peak, defined as having a LOD-score<LODmax-2 or LOD-score<LODmax-1. The Homozyg. line indicates whether the linkage peak was detected as a run of shared homozygosity by the KinSNP analysis.