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. 2012 Mar 13;7(3):e33358. doi: 10.1371/journal.pone.0033358

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Shi et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A, Table presentation of the tumorigenic potential of H460 SP and non-SP cells. Three parameters of tumorigenicity, i.e., tumor incidence, latency, and volume (*P<0.01) were shown. All animals were terminated (term.) 28 days after implantation. B, The SP cells regenerated larger tumors than corresponding non-SP cells at every cell dose. C, Gross tumor images when tumors were harvested at day 28 after s.c. injection of the SP and non-SP cells into NOD/SCID mice. D, Representative HE-stained photomicrographs of SP and non-SP tumors.