Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Mar 13;7(3):e33250. doi: 10.1371/journal.pone.0033250

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

PMC Copyright notice

A. Overall decline in the total cellular sulfhydryl content in the BEC followed both hypoxia (10% O₂×4 h) and ARSB silencing, consistent with the observed effect on the reduced glutathione and the overall change in the cellular redox state (p<0.001). Total sulfhydryl content is composed of inorganic and protein thiols, and the inorganic thiol did not change significantly, indicating that the change in total thiols was attributable to the protein-associated thiols. B. Similar decline in the thiol cellular sulfhydryl content occurred in the NCM460 cells following either hypoxia (10% O₂×4 h) or ARSB silencing (p<0.001). The inorganic thiol content did not change significantly, indicating that the change occurred in the protein thiol component. [BEC = bronchial epithelial cell; ARSB = arylsulfatase B].