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. 2012 Mar 13;7(3):e33250. doi: 10.1371/journal.pone.0033250

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A, B. The galectin-3 that co-immunoprecipitated with C4S in the BEC declined significantly following both hypoxia (10% O₂×4 h) and ARSB silencing (p<0.001), consistent with reduced association of galectin-3 with more highly sulfated C4S. C, D. Galectin-3 content in the nuclear fraction of the BEC increased significantly following both ARSB silencing and hypoxia (10% O₂×4 h) (p<0.001). [BEC = bronchial epithelial cell; ARSB = arylsulfatase B].