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. 2012 Mar 9;7(3):e33221. doi: 10.1371/journal.pone.0033221

Figure 7. Clinical usefulness of time-frequency analysis of chemosensory ERPs.

Figure 7

A. Time-frequency representation of the non-phase locked EEG responses to trigeminal and olfactory chemosensory stimulation (CWT-SINGLE; see Methods) in one hyposmic patient (TDI = 23) and one anosmic patient (TDI = 14). Signal amplitude is expressed as percentage increase or decrease relative to baseline (−0.4 to −0.1 s) (trigeminal stimulation: electrode Cz; olfactory stimulation: electrode Fz). B. Magnitude of TRI-TF1 and OLF-TF1 measured in the hyposmic patient (grey dot), the anosmic patient (white dot) and the 11 healthy controls (black dot). The horizontal red line indicates the cutoff amplitude value associated with the greatest Youden index. Note that the magnitude of OLF-TF1 measured in the hyposmic and anosmic patients are both below the cutoff value. In contrast, note that the magnitude of TRI-TF1 measured in the two patients was similar to those measured in the healthy controls.