Figure 3. Activated caspase 3 and Ki-67 in C. rodentium-induced liver lesions.

Control livers showed minimal staining for the apoptotic marker activated caspase 3, and proliferative marker Ki-67 (far left panels), while livers with necrosis at 3 DPI stained positively for both markers with a periportal pattern of distribution (middle (100×) and far right (200×)). Pictured is a representative liver section that was serially sectioned and immunostained independently for each cellular marker.