Skip to main content
. Author manuscript; available in PMC: 2013 Mar 28.
Published in final edited form as: Neurosci Lett. 2012 Feb 10;513(1):42–46. doi: 10.1016/j.neulet.2012.02.004

Figure 1. Characterization of oligodendrocyte precursor cells (OPCs) and brain endothelial cells.

Figure 1

(a) Immunostaining confirmed the expression of OPC markers A2B5 and NG2, but not astrocyte marker GFAP in our OPCs. (b) OPCs were functional because they were matured into myelin-basic-protein-positive oligodendrocytes after differentiation. (c) Primary human brain microendothelial cells expressed the endothelial markers CD31, vWF and VE-cadherin (VE-Cad) but not the smooth muscle cell marker alpha smooth muscle (αSM). (d) Cells expressed tight-junction proteins, claudin-5 and ZO-1. (e) In vitro angiogenesis assay confirmed that cells were capable to form vessel-like tubes.