. Author manuscript; available in PMC: 2013 May 1.

Published in final edited form as: J Autoimmun. 2011 Dec 3;38(2-3):J177–J186. doi: 10.1016/j.jaut.2011.11.007

Table 3.

Gender in animal models of autoimmunity

Animal Model	Autoimmune Disease	Gender Predominance
Spontaneous
MRL-Fas^lpr	SLE	None
MRL-Fas^+/+	SLE	None
(NZBxNZW)F1	SLE	Female
(NZBXSJL)F1	SLE	Female
(SWRxSJL)F1	SLE	Female
NZB	SLE, Autoimmune hemolytic anemia (AIHA)	Female (moderate)
NZM	SLE	Female NZM88, 2328, 391, 2758, 64
		No sex bias NZM2410
BXSB	SLE	Male
NOD	Type 1 diabetes	Female
Genetically modified
C1q deficient MRL-Fas^+/+	SLE	Female
C1q deficient MRL-Fas^lpr	SLE	None
Induced
EAE	Multiple sclerosis (MS)	Female SJL, A.SW, NZW Male B10.PL, PL/J No sex bias C57BL/6, NOD

See text for details.