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(a) The mechanism of target DNA detection by a PGM via the sandwich hybridization assay using Capt-DNA coated magnetic beads (MBs) and DNA-invertase conjugates. (b) DNA sequences used for a proof-of-concept model DNA (Target-DNA) detection. (c) DNA sequences used for a Hepatitis B virus (HBV) DNA fragment (Target-DNA-HBV) detection. The underlined nucleotides are the mismatch sites for controls.
