Table 1.
Organ weight (mg) | Control (n = 10) | Placebo (n = 28) | 25 mg kg−1 day−1 UDCA (n = 9) | 100 mg kg−1 day−1 UDCA (n = 10) |
---|---|---|---|---|
Heart | 781 ± 16.5 | 520 ± 17.2* | 509 ± 21* | 529 ± 33* |
Lung | 1,273 ± 69 | 864 ± 27* | 992 ± 71**, *** | 916 ± 43*, **** |
Liver | 10,600 ± 393 | 6,325 ± 265* | 6,798 ± 345* | 6,265 ± 684* |
Spleen | 641 ± 30 | 189 ± 30* | 206 ± 34* | 222 ± 57* |
Kidney left | 1,126 ± 31 | 708 ± 19.3* | 690 ± 32* | 717 ± 45* |
Kidney right | 1,162 ± 39 | 735 ± 22* | 724 ± 33* | 729 ± 42* |
WAT | 1,309 ± 151 | 87 ± 24* | 301 ± 155* | 438 ± 241***, **** |
BAT | 220 ± 12.1 | 83 ± 4.77* | 103 ± 8.6*, **** | 96 ± 14.0* |
M. gastrocnemius | 1,255 ± 42 | 725 ± 16.0* | 828 ± 81*, **** | 814 ± 81*, **** |
M. tibialis | 457 ± 12.4 | 268 ± 7.10* | 296 ± 23* | 300 ± 29* |
M. EDL | 107 ± 3.66 | 64 ± 1.51* | 71 ± 5.4*, **** | 68 ± 6.3* |
M. soleus | 98 ± 2.97 | 71 ± 1.60* | 79 ± 5.2***, **** | 69 ± 6.4* |
*p < 0.001 vs. control; **p < 0.05 vs. placebo; ***p < 0.01 vs. control; ****p < 0.12 vs. placebo