Table 3.

Effects of sActRIIB treatment on tumor mass and metastases in mice bearing the Lewis lung carcinoma

	T	T + A	ANOVA
Tumor weight (mg)	4,354 ± 213	3,790 ± 153	0.0497
Tumor volume (ml)	5.0 ± 0.33	4.2 ± 0.2	0.0492
Metastases number	6.2 ± 1.1	3.6 ± 0.8	ns
Metastases volume	29.9 ± 13.3	28.7 ± 11	ns
% Lung metastases	15.7 ± 6.7	19.9 ± 7.5	ns

Results are mean ± S.E.M. for eight animals. Statistically significant difference by post hoc Duncan test. Statistical significance of the results by one-way analysis of variance (ANOVA), treatment effect

T tumor-bearing mice, T + A tumor-bearing mice treated with sActRIIB, ns nonsignificant differences