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. 2011 Nov 8;3(1):37–43. doi: 10.1007/s13539-011-0049-z

Table 5.

Effects of sActRIIB treatment on muscle force in mice bearing the Lewis lung carcinoma

C T T + A
Grip force (day 0) 5.1 ± 0.21a,c 4.7 ± 0.20a,c 5.2 ± 0.24a,c
Grip force (day 14) 5.0 ± 0.23a,c 2.8 ± 0.16b,d 4.4 ± 0.3a,c

Grip force is expressed as grams per gram IBW. Results are mean ± S.E.M. Statistical significance of the results by one-way analysis of variance (ANOVA). Statistically significant difference by post hoc Duncan test. Different letters in superscript indicate significant differences between groups (a and b: differences between C, T, and T + A groups the same day of measurement; and c and d: differences between days 0 and 14 in the same group)

C control mice (n = 4), T tumor-bearing mice (n = 8), T + A tumor-bearing mice treated with sActRIIB (n = 8)