Table 2.
Comparison of gene expression changes in control and treated cells from different cellular models
| Up | Down | Either | Mean ± SD | |
|---|---|---|---|---|
| Control condition | ||||
| HH1.HH2 | 216 | 50 | 267 | 326 ± 72 |
| HH1.HH3 | 343 | 63 | 406 | |
| HH2.HH3 | 154 | 150 | 304 | |
| HH1.HepG2 | 611 | 113 | 724 | 599 ± 132 |
| HH2.HepG2 | 434 | 178 | 612 | |
| HH3.HepG2 | 326 | 135 | 461 | |
| HH1.HepaRG | 144 | 96 | 240 | 315 ± 66 |
| HH2.HepaRG | 133 | 230 | 363 | |
| HH3.HepaRG | 99 | 243 | 342 | |
| HepG2.HepaRG | 93 | 397 | 490 | 490 |
| Control vs. induced condition | ||||
| HepG2 | ||||
| DMSO.BNF | 31 | 61 | 92 | 73 ± 22 |
| DMSO.PB | 17 | 60 | 77 | |
| DMSO.RIF | 27 | 22 | 49 | |
| HepaRG | ||||
| DMSO.BNF | 106 | 25 | 131 | 85 ± 40 |
| DMSO.PB | 35 | 25 | 60 | |
| DMSO.RIF | 41 | 22 | 63 | |
| HH1 | ||||
| DMSO.BNF | 74 | 50 | 124 | 100 ± 21 |
| DMSO.PB | 46 | 44 | 90 | |
| DMSO.RIF | 26 | 61 | 87 | |
| HH2 | ||||
| DMSO.BNF | 64 | 81 | 145 | 131 ± 38 |
| DMSO.PB | 39 | 121 | 160 | |
| DMSO.RIF | 39 | 49 | 88 | |
| HH3 | ||||
| DMSO.BNF | 51 | 35 | 86 | 91 ± 13 |
| DMSO.PB | 76 | 29 | 105 | |
| DMSO.RIF | 59 | 22 | 81 | |
The table represents the number of differentially expressed probes among the different cellular models in the control condition (upper part) and after exposure to the different inducers (lower part). The differentially expressed probes have been defined as having a fold change of >2 for upregulated genes or <−2 for downregulated genes. Note that for any comparison noted AA.BB, the fold change is computed as the mean of the first group divided by the mean of the second group: mean (AA)/mean (BB)
SD standard deviation