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. 2012 Jan 19;28(2):69–87. doi: 10.1007/s10565-011-9208-4

Table 5.

Summary of CYP activity in the HH (3 donors), HepaRG, and HepG2 cells after exposure to vehicule, BNF, PB, and RIF

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CYP1A2, 2B6, and 3A4 activities were measured using ethoxyresorufin O-deethylase, bupropion hydroxylation (BPH), and midazolam as respective catalytic probes. Values in (a) represent the basal and induced activities; values in (b) represent the average fold change (technical triplicates) compared to vehicle treated cells. Standard deviation is indicated between brackets. Fold changes >2 and <5 are colored in yellow, >5 and <10 in orange, and >10 in red

ND no data reported for BPH activity due to technical problem, BLQ below detection limit