Figure 3. The effect of pyrvinium on MSC proliferation.
In vitro proliferation of MSCs treated with pyrvinium or compd 211 was evaluated by BrdU incorporation. Pyrvinium enhanced both mouse (A) and human (B) MSC proliferation. Data here shows average of the relative BrdU incorporation indicating MSC proliferation in the presence or absence of different treatments. The statistical significance between experimental groups and control was determined by ANOVA followed by Tukey’s multiple comparison test. *p<0.05 was considered statistically significant.