KB cells were transfected by non-PEGylated lipoplexes and formulations incorporating 0.4 mol% PEG–cholesterol or PEG-DSPE in 50% serum. The data represent the mean ± one standard deviation of three replicates.
*p < 0.05 when compared with the non-PEGylated control.
DOTAP: N-(1-[2,3-dioleoyloxy]propyl)-N,N,N-trimethylammonium chloride;
DSPE: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine.