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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Nat Genet. 2011 Sep 18;43(10):969–976. doi: 10.1038/ng.940

Figure 1.

Figure 1

Manhattan plot for stages 1 and 2. Standard −log10 P plot of the study results. For the stage 1 results, 16 regions with one or more SNP achieving P < 10−6 are highlighted in color and labeled with the name of the nearest gene. SNPs selected for stage 2 replication are highlighted, with the resulting combined P value after replication (that is, after incorporation of stage 2 results) indicated by the large diamonds. Blue highlighting indicates SNPs that were less significantly associated after replication, and pink highlighting indicates SNPs that were more significantly associated after replication.