Table 3.
Association between migraine and CAD from random effects model, heterogeneity, and small study effects
| Migraine status | No. of studies | Pooled effect estimates | Heterogeneity | Small study effects p-value | |||||
|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | p-value | Q | df | p-value | I2 in % | Begg test | Egger's test | ||
| Any migraine | |||||||||
| All studies | 5 (10–14) | 2.06 (1.33–3.19) | 0.001 | 9.0 | 4 | 0.06 | 55.5 | 0.14 | 0.81 |
| Women | 2 (10, 11) | 2.10 (1.27–3.47) | 0.004 | 0.3 | 1 | 0.56 | 0.0 | 0.32 | --- |
| Men | 2 (10, 11) | 2.18 (1.38–3.45) | 0.001 | 0.7 | 1 | 0.42 | 0.0 | 0.32 | --- |
|
| |||||||||
| Migraine with aura | |||||||||
| All studies | 5 (10–14) | 1.50 (0.76–2.96) | 0.24 | 7.7 | 4 | 0.10 | 48.2 | 1.00 | 0.31 |
| Women | 1 (10) | 2.79 (1.40–5.59) | --- | --- | --- | --- | --- | --- | --- |
| Men | 1 (10) | 2.21 (1.19–4.11) | --- | --- | --- | --- | --- | --- | --- |
|
| |||||||||
| Migraine without aura | |||||||||
| All studies | 5 (10–14) | 1.94 (1.21–3.10) | 0.006 | 8.0 | 4 | 0.09 | 49.8 | 0.14 | 0.40 |
| Women | 1 (10) | 1.60 (0.74–3.49) | --- | --- | --- | --- | --- | --- | --- |
| Men | 1 (10) | 1.75 (0.84–3.65) | --- | --- | --- | --- | --- | --- | --- |
OR: odds ratio; df: degrees of freedom.