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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Cancer Lett. 2011 Dec 11;318(1):99–105. doi: 10.1016/j.canlet.2011.12.007

Fig. 2.

Fig. 2

SiRNA-mediated repression of TRPM7 induced cellular morphology indicative of a senescent phenotype. BxPC-3 and PANC-1 cells transfected with anti-TRPM7 siRNA or non-targeting control siRNA were stained with hematoxylin and eosin, and examined under a compound light microscope. Arrows point at the enlarged cells containing multiple nuclei in both BxPC-3 and PANC-1 and cytoplasmic vacuoles in BxPC-3. Similar results were obtained in duplicate culture dishes and the experiment was repeated twice.