Table 1.
Relationship between APC promptor methylation and clinicopathology parameters in healthy controls and cases.
| Characteristics | Controls |
* APC Methylation status | P value | Cases |
APC methylation status | **P value |
||
|---|---|---|---|---|---|---|---|---|
| N = 57 | N=84 | |||||||
| Present N (%) |
Absent N (%) |
Present N (%) |
Absent N (%) |
|||||
| Mean age | 39.07 ± 14 | 54.14 ± 18 | ||||||
| < 50 | 46 | 39 (84.8) | 7 (15.2) | 26 | 20(76.93) | 6 (23.07) | ||
| 0.9 | 0.2 | |||||||
| > 50 | 11 | 10(90.90) | 1 (9.1) | 58 | 39(67.24) | 19(32.76) | ||
| Sex | ||||||||
| Male | 21 | 18 (85.7) | 3 (14.3) | 39 | 32(82.05) | 7 (17.95) | ||
| 0.06 | 0.72 | |||||||
| Female | 36 | 32(88.88) | 4 (11.12) | 45 | 28(62.22) | 17(37.78) | ||
| Stage | 0.05 | |||||||
| I | - | - | - | - | 18 | 11(61.11) | 7(38.89) | |
| II | 18 | 15(83.33) | 3(16.64) | |||||
| III | 43 | 31(72.08) | 12(27.92) | |||||
| IV | 5 | 2(40) | 3(60) | |||||
* Methylation present: means that PCR product is produced only with methylated primers.
Methylation absent: means that PCR product is produced only with unmethylated primers.
**Chi-square test