Table 1.
Body weight, blood glucose levels, pancreatic insulin content, and liver vitamin C content after 8 weeks of vitamin C deficiency (15 weeks of age)
| KO |
WT |
|||
|---|---|---|---|---|
| VC (+) | VC (−) | VC (+) | VC (−) | |
| Body weight (g) | 29.6 ± 0.6 | 31.4 ± 0.6 | 29.6 ± 0.9 | 30.1 ± 0.6 |
| Fasting blood glucose (mg/dl) | 99.7 ± 6.0 | 86.9 ± 5.7 | 82.6 ± 8.1 | 88.0 ± 3.1 |
| Fed blood glucose (mg/dl) | 145.1 ± 7.8 | 160.7 ± 6.2 | 142.7 ± 7.6 | 163.6 ± 7.3 |
| Pancreatic insulin content (µg/g tissue) | 44.4 ± 5.3 | 41.9 ± 3.4 | 38.6 ± 5.9 | 38.3 ± 4.9 |
| Vitamin C content, liver (µg/g tissue) | 143.7 ± 7.7 | 9.9 ± 1.3* | 169.4 ± 9.9 | 160.2 ± 8.5 |
KO: SMP30/GNL knockout mice. WT: wild type mice. VC (+): vitamin C-supplemented. VC (−): vitamin C-deficient. *p<0.01 vs VC (+) KO, VC (+) WT, and VC (−) WT. Data are means ± SE from seven mice.