Fig. 7.

Prx1 interacts with many proteins and exhibits many biological functions. Prx1 is the major Prx family protein and plays many functions through direct interaction with different types of proteins. Recent studies have established that Prx1 is not just an antioxidant in the cytoplasm, but it also regulates gene expression in nucleus and inflammatory reactions in extracellular space. In addition to these proteins, some kinases and phosphatases modify Prx1 and regulate its biological functions.