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. 2012 Feb 14;2012:904141. doi: 10.1155/2012/904141

Table 4.

Augmentation index.

Population N Therapy Study period mean ± SD min–max
Renal patients 6 N/A N/A# 26.1 ± 13.9* 13.3–52.0
Diabetic patients 8 Metformin cont 5.9 ± 9.4** −8.0–22.0
Diabetic patients 8 Metformin discont 14.3 ± 18.9** 1.0–55.0
Diabetic patients 8 Metformin + SA cont 9.0 ± 13.0∗∗, ∗∗∗ −15.0–24.0
Diabetic patients 8 Metformin + SA discont 16.3 ± 16.0∗∗, ∗∗∗ −6.0–32.0
Healthy volunteers 12 N/A N/A −6.0 ± 14.2 −25.7–31.7

SA: sulfonylurea; SD: standard deviation.

Cont: continuation of therapy; discount: 2 weeks of therapy discontinuation.

#visit 1, 2, and 3 and averaged (see materials and methods).

*P = 0.001 versus healthy volunteers.

**P < 0.05 versus healthy volunteers.

***P < 0.05 versus diabetic patients on metformin only.