Table 2.
Effects of single and repeated EEM administration on serum TC and TG levels in normal and diabetic mice.
| Group | Single administration | Repeated administration | ||
|---|---|---|---|---|
| TC (mmol/L) | TG (mmol/L) | TC (mmol/L) | TG (mmol/L) | |
| Normal control | 2.13 ± 0.20 | 0.74 ± 0.07 | 2.13 ± 0.16 | 0.75 ± 0.06 |
| Normal + 2 g/kg EEM | 2.11 ± 0.20 | 0.75 ± 0.11 | 2.14 ± 0.17 | 0.75 ± 0.06 |
| Normal + 4 g/kg EEM | 2.17 ± 0.22 | 0.77 ± 0.09 | 2.14 ± 0.20 | 0.74 ± 0.05 |
| Normal + 8 g/kg EEM | 2.08 ± 0.22 | 0.75 ± 0.08 | 2.10 ± 0.16 | 0.73 ± 0.06 |
| Normal + glibenclamide | 2.11 ± 0.21 | 0.75 ± 0.08 | 2.11 ± 0.14 | 0.74 ± 0.08 |
| Diabetic control | 3.47 ± 0.33* | 1.26 ± 0.12* | 3.49 ± 0.32* | 1.28 ± 0.09* |
| Diabetic + 2 g/kg EEM | 3.45 ± 0.39 | 1.24 ± 0.10 | 3.47 ± 0.26 | 1.24 ± 0.11 |
| Diabetic + 4 g/kg EEM | 3.44 ± 0.43 | 1.24 ± 0.12 | 2.92 ± 0.22# | 1.01 ± 0.11# |
| Diabetic + 8 g/kg EEM | 3.44 ± 0.31 | 1.25 ± 0.10 | 2.82 ± 0.25# | 0.97 ± 0.07# |
| Diabetic + glibenclamide | 3.48 ± 0.34 | 1.23 ± 0.10 | 3.46 ± 0.13 | 1.27 ± 0.09 |
Data are expressed as mean ± SD, n = 10 mice per group. *P < 0.01 when compared to normal control. # P < 0.01 when compared to diabetic control.