Figure 4.

Perturbation in TTV immune surveillance in asymptomatic HIV-1-infected patients. (a) Correlation between TTV and HIV-1 viral loads (log⁡ DNA copies/mL, and log⁡ RNA copies/mL, resp.) in plasma derived from asymptomatic HIV-1-infected patients. TTV and HIV viral loads were measured by PCR and RT-PCR, respectively. (b) Correlation between plasma TTV titer and percentage of CD10⁻CD21^lowCD27⁻ B cells in asymptomatic HIV-1-infected patients. Association of 2 different data groups were analyzed by Spearman's rank test; P and rho values are indicated. Each symbol represents one individual, and regression line is shown.