Table 3.
Effects of HAART on B cells frequency, IL-7 serum levels, and TTV viral load.
Healthy | Asymptomatic HIV-1 infected | HAART treated | P (HAART treated versus healthy) | P (HAART treated versus asymptomatic HIV-1 infected) | |
---|---|---|---|---|---|
CD19+ B cell count (cell/μL) | 143.0 | 129.5 | 232.5 | <0.01 | <0.005 |
CD21−CD27− B cell frequency (%) | 2.1 | 10.4 | 2.7 | NS | <0.0001 |
CD21−CD27+ B cell frequency (%) | 2.4 | 9.6 | 1.7 | NS | <0.0001 |
CD21+CD27+ B cell frequency (%) | 29.4 | 23.5 | 22.4 | <0.05 | NS |
CD21+CD27− B cell frequency (%) | 64.4 | 54.2 | 73.0 | NS | <0.0005 |
IL-7 serum level (pg/mL) | 1.7 | 12.9 | 2.0 | NS | <0.01 |
TTV plasma viremia (log DNA copies/mL) | 4.6 | 5.7 | 4.1 | NS | <0.001 |
NS: not significant.
Results are expressed as median.