Table 2.
24-hour urinary excretion of NGAL, IL-10, TGF-β1, and TNF-α in the study groups.a
| SLE patients | Controls | ||||
|---|---|---|---|---|---|
| Active nephritis | Renal | Non-renal | DC | NC | |
| Number | 24 | 34 | 8 | 14 | 12 |
| NGAL (mg/day) | 50.41 (199.93) | 49.05 (114.45) | 21.78 (12.42) | 13.94 (12.53) | 7.65 (7.64) |
| IL-10 (ng/day) | 2.34 (16.81) | 3.45 (21.06) | 10.03 (18.27) | 13.12 (15.99) | 5.40 (24.09) |
| TGF-β1 (ng/day) | 41.54 (75.59) | 23.82 (69.08) | 16.17 (16.13) | 15.57 (14.94) | 7.83 (6.39) |
| TNF-α (ng/day) | 6.01 (15.23) | 5.85 (17.63) | 20.49 (24.26) | 26.68 (39.04) | 0 (13.65) |
aData are shown as median (IQR).
NGAL: neutrophil gelatinase-associated lipocalin; IL-10: interleukin-10; TGF-β1: transforming growth factor-β1; TNF-α: tumor necrosis factor-α; SLE: systemic lupus erythematosus; DC: disease control; NC: normal control; IQR: interquartile range.