Table 1.
Risk of stroke or death from large-scale randomized trials comparing endovascular carotid artery stenting (CAS) and surgical carotid endarterectomy (CEA) treatment in patients with severe carotid-artery stenosis
| Patients | Any stroke or death at 30 days |
Disabling stroke or death at 30 days |
Ipsilateral stroke after 30 days |
||||
|---|---|---|---|---|---|---|---|
| CAS (n, %) | CEA (n, %) | CAS (n, %) | CEA (n, %) | CAS (n, %) | CEA (n, %) | ||
| CAVATAS87 | 504 | 25 (10.0) | 25 (9.9) | 16 (6.4) | 15 (5.9) | 6a | 10a |
| SAPPHIRE88 | 334 | 8 (4.8) | 9 (5.4) | n.a. | n.a. | n.a. | n.a. |
| SPACE89 | 1214 | 46 (7.7) | 38 (6.5) | 29 (4.8) | 23 (3.9) | 4 (0.7)b | 1 (0.2)b |
| EVA 3S90 | 527 | 25 (9.6) | 10 (3.9) | 9 (3.4) | 4 (1.5) | 2 (0.6)b | 1 (0.3)b |
| ICSSc91 | 1713 | 72 (8.5) | 40 (4.7) | 34 (4.0) | 27 (3.0) | 58 (6,8) | 30 (3.5) |
| CREST92 | 2502 | 55 (6.8) | 29 (3.6) | n.a. | n.a. | n.a. | n.a. |
n.a. = not available).
aFollow-up duration 1.95 years in mean.
bFollow-up duration up to 6 months.
cOutcome at 90 days (intention-to-treat data).