Table 3.
Inconsistent expression ratios of 5p arm miRNA to 3p arm miRNA between tissues
| Pre-miRNA | Location | N5p | N3p | Ratio_N53p | T5p | T3p | Ratio_T53p | Fold change |
|---|---|---|---|---|---|---|---|---|
| hsa-mir-17 | MA:14-36;mi:51-72 | 4,767 | 2,266 | 2.1037 | 6,656 | 425 | 15.6612 | 7.44 |
| hsa-mir-511-1 | 5p:16-36 | 39 | 903 | 0.0432 | 53 | 147 | 0.3605 | 8.35 |
| hsa-mir-511-2 | 5p:16-36 | 39 | 903 | 0.0432 | 53 | 147 | 0.3605 | 8.35 |
| hsa-mir-423 | 5p:17-39;3p:53-75 | 20,920 | 8,945 | 2.3387 | 1,708 | 6,266 | 0.2726 | 8.58 |
| hsa-mir-30c-1 | MA:17-39;mi:56-77 | 67,040 | 50 | 1,340.8000 | 8,685 | 64 | 135.7031 | 9.88 |
| hsa-mir-135b | MA:16-38;mi:55-76 | 360 | 19 | 18.9474 | 171 | 99 | 1.7273 | 10.97 |
| hsa-mir-376a-1 | mi:7-28;MA:44-64 | 1,646 | 14 | 117.5714 | 569 | 54 | 10.5370 | 11.16 |
| hsa-mir-376a-2 | 3p:50-70 | 428 | 14 | 30.5714 | 99 | 54 | 1.8333 | 16.68 |
| hsa-mir-335 | MA:16-38;mi:52-73 | 3,509 | 110 | 31.9000 | 418 | 264 | 1.5833 | 20.15 |
| hsa-mir-30b | MA:17-38;mi:55-76 | 50,988 | 51 | 999.7647 | 3,931 | 89 | 44.1685 | 22.64 |
Location column denotes the relative locations of mature miRNAs within their precursors. N5p, T5p individually denote the expression levels of 5p arm miRNA (determined by summing the read counts of all its isomiRs) in normal and tumor tissue; while, N3p, T3p denote the corresponding information of 3p arm miRNA. The N5p and N3p values shown in this study are normalized.