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. 2012 Mar 4;2012:543062. doi: 10.1155/2012/543062

Figure 5.

Figure 5

(a) Perivascular fibrosis of adult SHRs treated with vehicle (control, n = 6), candesartan cilexetil (2 mg/kg/day) alone (n = 7) or in combination with PD123319 (10 mg/kg/day, n = 7), or PD123319 alone (n = 7). (b) Perivascular fibrosis of senescent SHRs treated with vehicle (control, n = 10), candesartan cilexetil alone (n = 9) or in combination with PD123319 (n = 9), PD123319 alone (n = 4), or hydralazine (30 mg/kg/day, n = 7). Perivascular fibrosis of intramyocardial arterioles, calculated as cross-sectional area of adventitia to lumen ratio. *P < 0.05 versus control (1-way ANOVA).