Table 1. Characteristics of 494 obese patients included in each population.
Characteristics | Lille n = 288 | Paris n = 114 | Bethune n = 92 | All n = 494 |
Female sex: No (%) | 220 (76.4%) | 89 (78.1%) | 73 (79.4%) | 382 (77.3%) |
Age (years): mean (SD) | 41.6 (12.8) | 43.7 (11.3) | 43.6 (10.1) | 42.2 (11.3) |
BMI (kg/m2): mean (SD) | 48.6 (8.9) | 46.5 (7.6) | 45.1 (6.1) | 47.4 (7.9) |
Diabetes mellitus: No (%) | 92 (31.9%) | 38 (33.3%) | 11 (12.0%) | 141 (28.5%) |
Arterial hypertension : No (%) | 174 (60.4%) | 11 (61.1%) out of 181 | 32 (34.8%) | 217 (54.5%) out of 3981 |
Dyslipidemia No (%) | 167 (58.0%) | 43 (46.2%) out of 931 | 18 (19.6%) | 228 (48.2%) out of 4731 |
Cholesterolemia (g/l): mean (SD) | 4.94 (0.88) | 5.01 (0.98) | 5.81 (1.07) | 5.11 (1.00) |
Serum triglycerides (g/l): mean (SD) | 1.58 (0.88) | 1.61 (0.97) | 1.62 (0.75) | 1.60 (0.88) |
ALT (IU/l): mean (SD) | 34 (23) | 42 (33) | 35 (26) | 36 (26.5) |
GGT (IU/l): mean (SD) | 44 (48) | 58 (98) | 45 (85) | 47 (70) |
Fasting blood glucose (g/l): mean (SD) | 6.2 (2.4) | 6.1 (2.7) | 5.5 (2.0) | 6.0 (2.2) |
Biopsy length (mm) mean (SD) | 13.6 (11.0) out of 2621 | 16.3 (7.1) out of 211 | not available | 13.8 (10.8) out of 2831 |
Fibrosis F0/F1/F2/F3/F4: No (%) (METAVIR scoring system) | 170 (59.0%)/98 (34.0%)/13 (4.5%)/2 (0.7%)/5 (1.7%) | 48 (42.1%)/43 (37.7%)/16 (14.0%)/5 (4.4%)/2 (1.8%) | 22 (23.9%)/64 (69.6%)/0 (0%)/5 (5.4%)/1(1.1%) | 240 (48.6%)/205 (41.5%)/29 (5.8%)/12 (2.4%)/8 (1.6%) |
Inflammation I0/I1/I2/I3 (Kleiner score) | 196 (71.3%)/64 (23.3%)/11 (4.0%)/4 (1.5%) out of 2751 | 48 (42.1%)/60 (52.6%)/6 (5.3%) | 57 (62.0%)/32 (34.8%)/3 (3.3%) | 301 (62.6%)/156 (32.4%)/20 (4.2%)/4 (0.8%) out of 4811 |
Ballooning B0/B1/B2: No (%) (Kleiner score) | 237 (86.2%)/24 (8.7%)/14 (5.1%) out of 2751 | 41 (36.0%)/44 (38.6%)/29 (24.4%) | 27 (29.4%)/43 (46.7%)/22 (23.9%) | 282 (57.1%)/127 (25.7%)/85 (17.2%) out of 4811 |
Steatosis S0/S1/S2–S3 (Kleiner score) | 36 (12.5%)/113 (39.2%)/139 (48.3%) | 20 (17.5%)/32 (28.1%)/62 (54.4%) | 13 (14.1%)/29 (31.5%)/50 (54.4%) | 69 (14.0%)/157 (31.8%)/268 (54.2%) |
Extent of steatosis (%): mean (SD) | 31.2 (24.9) | 41.7 (33.7) | 40.9 (28.3) | 35.4 (28.2) |
NAS score (Kleiner) | ||||
0–2 No Nash | 203 (72.6%) | 40 (35.1%) | 39 (42.4%) | 282 (57.1%) |
3–4 Possible | 63 (20.4%) | 34 (29.8%) | 30 (32.6%) | 127 (25.7%) |
5–8 Nash | 22 (6.9%) | 40 (35.1%) | 23 (25.0%) | 85 (17.2%) |
When data are missing the number of patients with data not missing is given.