Table 3. Sensitivity, specificity and predictive values of biomarkers according to predetermined cutoffs in 494 patients with morbid obesity.
Biomarker (cutoff) | Disease (Prevalence) | Se | NPV | Sp | PPV |
FibroTest (0.27) | >F0 (51.4%) | 34/118 13.4%1 | 234/454 51.5% | 234/240 97.5% | 34/40 85.0% |
FibroTest (0.48) | >F1 (9.9%) | 4/49 8.2% | 443/488 90.8% | 443/445 99.6% | 4/6 66.7% |
SteatoTest (0.38) | >S0 (86.0%) | 381/425 89.7% | 31/75 41.3% | 31/69 44.9% | 381/419 90.9% |
SteatoTest (0.69) | >S1 33% (54.3%) | 103/268 38.4% | 184/349 52.7% | 184/226 81.4% | 103/145 71.0% |
NashTest (0.70) | NAS>4 (17.2%) | 12/85 14.1% | 392/465 84.3% | 392/409 95.8% | 12/29 41.4% |
NashTest (0.50) | NAS>2 (42.9%) | 197/212 92.9% | 95/110 86.4% | 95/282 33.7% | 197/384 51.3% |
ActiTest (0.29) | NAS>4 (17.2%) | 24/85 28.2% | 371/432 85.9% | 371/409 90.7% | 24/62 38.7% |
ActiTest (0.17) | NAS>2 (42.9%) | 92/212 43.4% | 241/361 66.8% | 241/282 85.5% | 92/133 69.2% |
number of patients n/N and %.