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. 2012 Mar 14;7(3):e30325. doi: 10.1371/journal.pone.0030325

Table 3. Sensitivity, specificity and predictive values of biomarkers according to predetermined cutoffs in 494 patients with morbid obesity.

Biomarker (cutoff) Disease (Prevalence) Se NPV Sp PPV
FibroTest (0.27) >F0 (51.4%) 34/118 13.4%1 234/454 51.5% 234/240 97.5% 34/40 85.0%
FibroTest (0.48) >F1 (9.9%) 4/49 8.2% 443/488 90.8% 443/445 99.6% 4/6 66.7%
SteatoTest (0.38) >S0 (86.0%) 381/425 89.7% 31/75 41.3% 31/69 44.9% 381/419 90.9%
SteatoTest (0.69) >S1 33% (54.3%) 103/268 38.4% 184/349 52.7% 184/226 81.4% 103/145 71.0%
NashTest (0.70) NAS>4 (17.2%) 12/85 14.1% 392/465 84.3% 392/409 95.8% 12/29 41.4%
NashTest (0.50) NAS>2 (42.9%) 197/212 92.9% 95/110 86.4% 95/282 33.7% 197/384 51.3%
ActiTest (0.29) NAS>4 (17.2%) 24/85 28.2% 371/432 85.9% 371/409 90.7% 24/62 38.7%
ActiTest (0.17) NAS>2 (42.9%) 92/212 43.4% 241/361 66.8% 241/282 85.5% 92/133 69.2%
1

number of patients n/N and %.