Table 1. Clinical patients’ characteristics.

Parameters	Overall populationn = 100	Septicn = 37 (37%)	Non-Septicn = 63 (63%)	p value
Age (years)	37±17	35±16	38±17	.34 *
Male,% (n)	73% (n = 73)	81% (n = 30)	68% (n = 43)	.24 ♦
ISS	37±10	39±8	35±10	.06 *
Severe brain injury,% (n)	38% (n = 38)	57% (n = 21)	27% (n = 17)	.006 ♦
Severe thoracic injury,% (n)	74% (n = 74)	62% (n = 23)	81% (n = 51)	.07 ♦
SAPS II	36.4±15.4	42.5±15.8	32.8±14.1	.002 *
Need for vasoactive support in emergency room,% (n)	26% (n = 26)	38% (n = 14)	19% (n = 12)	.07 ♦
Prophylactic antibiotics administrated in emergency room,% (n)	42% (n = 42)	38% (n = 14)	44% (n = 28)	.66 ♦
SOFA score
D1	4 [2]; [7]	7 [4.25; 10]	3[2]; [5]	<.0001 ‡
D2	4 [2]; [6]	6[3.5; 10]	2.5 [1]; [5]	<.0001 ‡
D3	3 [2]; [6]	7 [3.5; 9]	2 [1]; [3]	<.0001 ‡
D4	3 [1]; [5]	5.5 [2.5; 8]	2 [1]; [3]	<.0001 ‡
D5	2 [1]; [4]	5 [1.5; 7.5]	1 [1]; [3]	<.0001 ‡
D6	1 [1]; [4]	4 [1.5; 7]	1 [1]; [2]	<.0001 ‡
Shock (need for vasoactive drug on D1–2),% (n)	35% (n = 35)	59% (n = 22)	21% (n = 13)	.0002 ♦
Mechanical ventilation (MV),% (n)	66% (n = 66)	89% (n = 33)	52% (n = 33)	.0004 ♦
Duration of MV, days	6 [3]; [12]	10 [6]; [19]	3 [2; 5.25]	<.0001 ‡
Massive transfusion required,% (n)	32% (n = 32)	40% (n = 15)	27% (n = 17)	.24 ♦
Volume of global transfusion, ml	900 [0; 3,050]	1,800 [150; 4,300]	0 [0; 2,700]	.02 ‡
Length of stay in ICU, days	9.5 [6]; [15]	15 [10.75; 24.25]	7 [5; 10.75]	<.0001 ‡
Non-survivors at day 28,% (n)	5% (n = 5)	8% (n = 3)	3% (n = 2)	.06 ♦

Parametric variables are expressed as mean ± standard deviation, and non-parametric variables as median (interquartile range) or frequencies.

*Independent samples t-test.

^‡Mann & Whitney test.

^♦Chi-square test

Abbreviations: ISS, Injury Severity Score; SAPS, Simple Acute Physiology Score; SOFA, Sequential Organ Failure Assessment; HLA, Human Leukocyte Antigen; ICU, Intensive Care Unit; D, day; IL, Interleukin.