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. 2012 Mar 14;7(3):e33666. doi: 10.1371/journal.pone.0033666

Table 1. SNP associations with preeclampsia (p≤10−6).

Chr SNP bp1 Function Gene Alleles2 MAF(cases) MAF(controls) P-value OR3 (95% CI)
2 rs7579169 121118124 intergenic C/T 0.4471 0.3401 3.58×10−7 1.57 (1.32–1.87)
2 rs12711941 121123383 intergenic G/T 0.4482 0.3420 4.26×10−7 1.56 (1.31–1.86)
15 rs2453274 44774202 intronic CTDSPL2 C/T 0.0462 0.0989 2.32×10−6 0.44 (0.31–0.62)
13 rs12431203 77488736 intergenic G/A 0.2061 0.1303 2.45×10−6 1.73 (1.38–2.18)
21 rs2826538 22188735 intergenic T/C 0.1954 0.2782 5.93×10−6 0.63 (0.52–0.77)
2 rs9332419 26322040 intronic RAB10 G/A 0.3562 0.4518 6.17×10−6 0.67 (0.56–0.80)
2 rs4952830 46746963 UTR-5 ATP6V1E2 A/G 0.3343 0.4284 6.74×10−6 0.67 (0.56–0.80)
2 rs6542736 108415702 intergenic G/A 0.4094 0.3167 7.31×10−6 1.50 (1.25–1.79)
1 rs6660579 224916592 intronic CNIH3 C/T 0.1558 0.0924 7.80×10−6 1.81 (1.39–2.36)
3 rs2279720 87276699 synonymous CHMP2B G/A 0.0592 0.1128 8.66×10−6 0.49 (0.36–0.68)
3 rs1044499 87299075 synonymous CHMP2B A/C 0.0592 0.1128 8.66×10−6 0.49 (0.36–0.68)
2 rs11126375 26344787 intronic RAB10 A/G 0.1645 0.2412 9.13×10−6 0.62 (0.50–0.77)
4 rs7677523 98965696 intronic C4orf37 T/C 0.0833 0.0379 9.51×10−6 2.31 (1.58–3.37)
3 rs17024019 87257423 intergenic A/G 0.0601 0.1137 9.57×10−6 0.50 (0.36–0.68)
1

Physical coordinate based on NCBI reference assembly build 37.2.

2

Major allele/minor allele.

3

Odds ratio for the minor allele.