Table 2.

Effect of topical administration of hydrogel containing 100 μg per mL isolectin Cramoll 1,4 on the biochemical parameters of Wistar rats. Doses performed in triplicate for each parameter. G1 = Treatment, G2 = Control. Mean ± SD (n = 2).

Parameters	7th day		14th day		21st day		28th day		35th day
	G1	G2	G1	G2	G1	G2	G1	G2	G1	G2
Prothrombin time %	10.1 ± 0.07	9.7 ± 0.02	9.62 ± 0.11	10.1 ± 0.21	9.2 ± 0.21	10.1 ± 0.28	10.5 ± 0.71	10.1 ± 0.436	10.5 ± 0.70	9.7 ± 0.56
Fibrinogen mg/dL	460.5 ± 0.71	457.9 ± 0.07	407.1 ± 0.14	460.8 ± 0.21	412 ± 0.71	465.6 ± 0.47	380 ± 0.92	440.1 ± 0.142	407.7 ± 0.41	462.2 ± 0.34
Calcium mg/dL	10.3 ± 0.14	9.6 ± 0.46	8.4 ± 0.98	9.6 ± 0.42	11.6 ± 0.14	9.4 ± 0.16	11.5 ± 0.71	11.5 ± 0.658	9.7 ± 0.59	10.1 ± 0.42
Alkaline phosphatase U/L	193.6 ± 0.56	199.6 ± 0.49	212.7 ± 0.42	201.4 ± 0.57	208 ± 0.71	198.2 ± 0.31	275 ± 0.71	244.6 ± 0.601	209.7 ± 0.38	219.6 ± 0.62
Gamma glutamyl transferase U/L	5 ± 00	5.9 ± 0.14	5.7 ± 0.35	5.7 ± 0.29	5.8 ± 0.14	5.9 ± 0.02	5.3 ± 0.07	5.2 ± 0.012	5.6 ± 0.14	6.1 ± 0.72
Oxalic transaminase glutamic U/L	142 ± 0.07	176.6 ± 0.54	136.5 ± 0.71	208.2 ± 0.33	193 ± 0.71	179.9 ± 0.04	141.5 ± 0.64	156.6 ± 0.506	177.9 ± 0.15	178.8 ± 0.31
Transaminase glutamico piruvica U/L	60.7 ± 0.42	50.8 ± 0.19	55.7 ± 0.04	54.5 ± 0.58	47 ± 0.42	48.7 ± 0.33	48.5 ± 0.63	51.9 ± 0.129	58.5 ± 0.71	60.5 ± 0.78
Urea mg/dL	46.3 ± 0.49	46.9 ± 0.05	43.7 ± 0.35	50.6 ± 0.91	40 ± 0.71	45.9 ± 0.06	41.5 ± 0.71	46.8 ± 0.331	37.9 ± 0.11	41.5 ± 0.68
Creatinine mg/dL	0.2 ± 0.07	0.6 ± 0.04	0.5 ± 0.07	0.6 ± 0.12	0.4 ± 0.07	0.6 ± 0.01	0.6 ± 0.04	0.50 ± 0.011	0.5 ± 0.14	0.4 ± 0.04
Amylase U/L	838 ± 0.14	846.6 ± 0.56	789 ± 0.71	866.7 ± 0.42	808.3 ± 0.87	887.5 ± 0.71	856.6 ± 0.84	799.7 ± 0.469	814.5 ± 0.71	809.8 ± 0.27