Table 1.
Product distribution for the reduction of NOR and TIB catalyzed by AKR1C isoforms
3α – OH : 3β –OH | ||||
---|---|---|---|---|
AKR1C1 | AKR1C2 | AKR1C3 | AKR1C4 | |
NOR | 1 : 31 | 1 : 26 | 1 : 5.7 | 6.3 : 1 |
TIB | 3β only | 3β only | 1 : 5.4 | 4.7 : 1 |
Values for TIB were from reference [11], which were calculated based on radiometric assay.