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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Aging Cell. 2011 Dec 28;11(2):223–227. doi: 10.1111/j.1474-9726.2011.00775.x

Table 1.

Characteristics of the study cohorts investigated for the 2 TERC and 4 TERT candidate SNPs
The Cohorts
UT LSADT 1905 DLCS
Mean age at intake (years (range)) 68.2 (58.8–80.9) 78.8 (73.3–94.2) 93.2 (92.4–93.7) 100 (99.1–100.3)
Females (%) 100 66.1 82.3 77.1
N (2 TERC candidate SNPs): 213 547 125 128
MAF of rs12696304 0.28 0.28 0.28 0.33
MAF of rs3772190 0.26 0.26 0.25 0.33
N (4 TERT candidate SNPs) 213 549 175 132
MAF of rs2853691 0.32 0.37 0.39 0.35
MAF of rs33954691 0.11 0.11 0.12 0.11
MAF of rs2736098 0.32 0.24 0.25 0.25
MAF of rs2853669 0.36 0.28 0.29 0.29
N (mTRFL) 214 468 119 63
Mean age at mTRFL assessment (years) 68.2 79.3 99.7 102.2
mTRFL ± SD 6.25±0.042 5.71 ±0.023 5.20±0.043 5.18±0.06

Notes: UT: Unilever Twin Cohort Study, LSADT: the Longitudinal Study of Aging Danish Twins, 1905: the Danish 1905 Birth Cohort Study, DLCS: the Danish Longitudinal Centenarian Study, MAF: minor alleleb frequency, mTRFL: mean terminal restriction fragment length (LTL), SD: standard deviation.