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. Author manuscript; available in PMC: 2012 Mar 15.
Published in final edited form as: Vaccine. 2010 Jul 12;28(31):4997–5004. doi: 10.1016/j.vaccine.2010.05.023

Fig. 1. Immunization with rAd-A27L IM is protective against lethal vaccinia virus challenge in mice.

Fig. 1

6 – 8 week old Balb/c mice were immunized with 1×109 pfu of rAd. Vaccines encoding poxvirus glycoproteins were tested individually. Immunized mice were challenged i.n. with 5LD50 VV-WR at 4 weeks post vaccination and weighed at challenge and daily thereafter. Loss of body mass was used as a measure of morbidity. Mice that sustained more than 30% loss of body mass as shown by data points below the dotted line (B) were euthanized. Survival (A) and weight loss (B) are shown as mean values within each group ± SEM.