Figure 2.
Species-specific restriction by TRIM5α. “Yes” denotes restriction. “Weak” denotes weak restriction. “No” denotes no restriction. “N. D.” denotes no result has yet been published. P and Q/A indicate human immunodeficiency virus type 2 (HIV-2) with proline and glutamine/alanine residues at position 120 of the capsid protein, respectively (Song et al., 2007). HIV-1: human immunodeficiency virus type 1 (Yap et al., 2004; Song et al., 2005a; Stremlau et al., 2005); SIVmac: simian immunodeficiency virus isolated from a macaque; SIVsm: simian immunodeficiency virus isolated from sooty mangabey (Kirmaier et al., 2010); N-MLV: N-tropic murine leukemia virus (Ohkura et al., 2006); B-MLV: B-tropic murine leukemia virus (Ohkura et al., 2006); AGM: CV1 (Nakayama et al., 2005); or Vero cells (Kim et al., 2011) from African green monkey. Rhesus monkey TFP and Q alleles (Stremlau et al., 2004; Ylinen et al., 2005; Ohkura et al., 2006; Kono et al., 2008; Wilson et al., 2008a; Kirmaier et al., 2010), cynomolgus monkey (Nakayama et al., 2005; Song et al., 2007), owl monkey TRIMCyp (Nisole et al., 2004; Sayah et al., 2004; Virgen et al., 2008), pig-tailed monkey TRIMCyp (Brennan et al., 2008; Virgen et al., 2008; Kuang et al., 2009), rhesus monkey TRIMCyp (Wilson et al., 2008b; Kirmaier et al., 2010), and the major and minor haplotypes of CM TRIMCyp (TRIMCypDK and TRIMCypNE, respectively; Ylinen et al., 2010; Dietrich et al., 2011; Saito et al., 2012) are also included.