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. 2012 Mar 15;3:97. doi: 10.3389/fmicb.2012.00097

Figure 4.

Figure 4

Amino acid variation in HIV-2/SIV capsid (CA). (Upper) A phylogenetic tree of amino acid sequences of capsid of the HIV-2 (shaded area) or SIV isolates obtained from the Los Alamos database. P, Q, A, and G indicate amino acid residue 120 of GH123 or the corresponding position of each virus. (Lower) Filled arrows indicate the possible evolution of amino acid residue 120 of SIV or HIV-2 capsid proteins in humans (shaded area). Open arrows indicate the effects on viral load. Boxes show the codons of glutamine (Gln, Q), proline (Pro, P), alanine (Ala, A), and glycine (Gly, G).