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TRIM5α and TRIMCyp. (A) Diagram indicating splicing of TRIM5α or TRIMCyp in New World monkey (NWM) and Old World monkeys (OWMs). Non-coding and coding exons and cyclophilin A (CypA) sequences are shown in gray, black, and red, respectively. (B) The RING (R), B-box2 (B), coiled-coil (CC), PRYSPRY, and CypA domains of TRIM5α and TRIMCyp proteins are indicated by squares.
