Figure 3.

Panels A and B represent data from patients not previously exposed to clopidogrel (n = 42) who received a clopidogrel 600 mg loading dose prior to coronary intervention and data are grouped according to PON1 genotype (QQ192 vs QR/RR192). (A) Light transmittance aggregometry before and at 4 and 16–24 hours after a 600 mg loading dose of clopidogrel; (B) platelet inhibition (percent change from baseline measurement) at 4 and 16–24 hours after a clopidogrel 600 mg loading dose.

Note: Values represent the mean plus or minus the standard error of the mean.

Abbreviation: ADP, adenosine diphosphate.