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. 2010;18(3):179–184.

Table 2.

binding constant, K, the number of binding sites, n, and the thermodynamic parameters for the association of Erlotinib hydrochloride with BSA.

pH T(K) Ka(1mol−1)×10−4 n △H (kJ mol−1) △G (kJ mol−1) △S (J mol−1)
7.4 298 2.9882 1.1165 38.910 −25.838 217.278
303 5.4250 1.2357 −26.924
308 5.6809 1.0457 −28.011
313 6.9838 0.9692 −29.097