Skip to main content
. 2012 Feb 23;106(6):1095–1099. doi: 10.1038/bjc.2012.39

Table 1. Univariate and multivariate analysis for death from prostate cancer.

  Univariate analysis
Multivariate analysis
Variable N χ2 (1 df) Hazard ratio (95% CI) P-value N χ2 (1 df) Hazard ratioa (95% CI) P-value
CCP score 349 37.6 2.02 (1.62, 2.53) 8.6 × 10−10 349 17.7 1.65 (1.31, 2.09) 2.6 × 10−5
Gleason score
 <7 106 36.4 0.46 (0.25, 0.86) 1.6 × 10−9 106 12.1 0.61 (0.32, 1.16) 5.0 × 10−4
 7 152   1 (ref)   152   1 (ref)  
 >7 91   2.70 (1.72, 4.23)   91   1.90 (1.18, 3.07)  
log (1+PSA) (ng ml−1) 349 16.8 1.70 (1.31, 2.20) 4.2 × 10−5 349 5.7 1.37 (1.05, 1.79) 0.017
Extent of disease b
 <50% 69 14.1 0.50 (0.22, 1.12) 0.0002        
 50–<100% 106   1 (ref)          
 100% 160   1.66 (1.01, 2.73)          
                 
Age at diagnosis (years) 349 0.05 1.00 (0.96, 1.04) 0.82        
Clinical stage
 T1 38 3.72 0.75 (0.32, 1.75) 0.054        
 T2 106   1 (ref)          
 T3 43   1.74 (0.90, 3.38)          
Hormone use
 No 200 10.2 1 (ref) 0.001        
 Yes 149   1.97 (1.30, 2.98)          

Abbreviations: χ2=chi-square; df=degrees of freedom; CI=confidence interval; ref=reference category; PSA=prostate-specific antigen.

a

Gleason score assessed with 2df for computing the hazard ratios in the multivariate analysis.

b

Proportion of positive cores.