Table 4. Molecular predictors of non-invasive (DCIS) local recurrence.

	N	No of DCIS LR	Hazard ratio (95% CI)	P-value
Univariable analysis
HER2/neu+			2.72 (1.26, 5.88)	0.01
Psoriasin (⩾10%)			1.30 (0.52, 3.24)	0.57
Calgranulin (⩾10%)			1.47 (0.62, 3.49)	0.39
Ki67 (⩾10%)			1.05 (0.47, 2.35)	0.91
p53 (⩾10%)			0.89 (0.40, 1.99)	0.77
ER positive			1.14 (0.48, 2.71)	0.77
PR positive			0.71 (0.33, 1.53)	0.37
Cyclin D1 (⩾10%)			1.01 (0.99, 1.02)	0.52
p21 (⩾10%)			1.24 (0.57, 2.71)	0.58
Multivariable analysis (adjusted for age and XRT)
Her2/neu+	58	13	2.67 (1.23, 5.79)	0.01
HER2/neu+/Ki67+ (vs other)	51	10	3.22 (1.47, 7.03)	0.003
HER2/neu+/Ki67− (vs other)	7	0	Not calculable
HER2/neu+/p53+(vs other)	35	5	1.54 (0.61, 3.91)	0.36
Ki67+/p53+ (vs other)	63	6	1.09 (0.44, 2.67)	0.86
HER2/neu+/Ki67+/p53+ (vs other)	31	5	1.79 (0.70, 4.57)	0.22
ER−/HER2/neu+/Ki67+ (vs other)	31	6	1.65 (0.66, 4.15)	0.28