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. 2012 Feb 23;106(6):1160–1165. doi: 10.1038/bjc.2012.41

Table 5. Molecular predictors of invasive recurrence.

Univariable analysis N No of Inv LR Hazard ratio (95% CI) P-value
HER2/neu+     1.58 (0.69, 3.62) 0.28
Psoriasin (⩾10%)     0.38 (0.09, 1.60) 0.19
Calgranulin (⩾10%)     1.24 (0.49, 3.12) 0.65
Ki67 (⩾10%)     0.79 (0.35, 1.77) 0.56
p53 (⩾10%)     0.88 (0.38, 2.06) 0.77
ER positive     0.64 (0.29, 1.45) 0.29
PR positive     1.30 (0.55, 3.03) 0.55
Cyclin D1 (⩾10%)     0.99 (0.98, 1.01) 0.85
p21 (⩾10%)     0.85 (0.38, 1.90) 0.69
         
Multivariable analysis (adjusted for age and XRT)        
 HER2/neu/neu+ 58 9 1.61 (0.70, 3.73) 0.26
 HER2/neu+/Ki67+ (vs other) 51 6 1.33 (0.54, 3.28) 0.54
 HER2/neu+/Ki67− (vs other) 7 2 1.22 (0.29, 5.06) 0.79
 HER2/neu+/p53+(vs other) 35 3 1.04 (0.35, 3.11) 0.94
 Ki67+/p53+ (vs other) 63 6 1.41 (0.57, 3.52) 0.46
 HER2/neu+/Ki67+/p53+ (vs other) 31 3 1.22 (0.40, 3.69) 0.73
 ER−/HER2/neu+/Ki67+ (vs other) 31 5 1.39 (0.51, 3.78) 0.52